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本帖最后由 hbv8312 于 2010-12-30 13:00 编辑
找战友带的印度CIPLA产的TENVIR-EM刚拿到了哈.
目前只有三盒.....包装相当简单,里面就一张纸,盒子质量也不咋的,不过只要药管用就好!
这个是30粒/瓶,500mg/粒,其中富马酸泰诺福韦酯-300mg(相当于替诺福韦酯245mg),Emtricitabine 200mg.
刚注意到说明书:
(还没有被批准用于治疗HBV,安全和有效性没有得到证实,有服用替诺福韦等核甘药物的死亡案例)
WARNING ACTIC ACIDOSIS/SEVERE HEPATOMEGALY WITH STEATOSIS
and POST TREATMENT ACUTE EXACERBATION OF HEPATITIS B
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS,
INCLUDING FATAL CASES, HAVE BEEN REPORTED WITH THE USE OF
NUCLEOSIDE ANALOGS, INCLUDING TENOFOVIR, A COMPONENT OF
TENVIR-EM, IN COMBINATION WITH OTHER ANTIRETROVIRALS (SEE
WARNINGS AND PRECAUTIONS).
TENVIR-EM IS NOT APPROVED FOR THE TREATMENT OF CHRONIC
HEPATITIS B VIRUS (HBV) INFECTION AND THE SAFETY AND EFFICACY
OF TENVIR-EM HAVE NOT BEEN ESTABLISHED IN PATIENTS COINFECTED
WITH HBVAND HIV-1. SEVERE ACUTE EXACERBATIONS OF HEPATITIS B
HAVE BEEN REPORTED IN PATIENTS WHO ARE COINFECTED WITH HBV
AND HIV-1 AND HAVE DISCONTINUEDTENOFOVIR/EMTRICITABINE.
HEPATIC FUNCTION SHOULD BE MONITORED CLOSELY WITH BOTH
CLINICAL AND LABORATORY FOLLOW-UP FOR AT LEAST SEVERAL
MONTHS IN PATIENTS WHO ARE COINFECTED WITH HIV-1 AND HBV AND
DISCONTINUETENVIR-EM. IF APPROPRIATE, INITIATION OF ANTIHEPATITIS
B THERAPY MAY BE WARRANTED (SEE WARNINGS AND
PRECAUTIONS).
DOSAGE AND ADMINISTRATION
The dosage of TENVIR-EM is one tablet (containing 200 mg of emtricitabine and 300
mg of tenofovir DF) once daily taken orally with or without food.
(没有要求要和食物一起服用啊.Orally with or without food,之前有说要求跟食物一起服用?)
明天去查DNA,两对半定量,肝功周一查的是ALT 70, AST 47,其他正常....
要是阴了就不用药了......但是也想试试这药的效果如何!
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发表于 2010-12-30 12:04
